Search and arrest
The right of the people to be secure in their persons, houses, papers, and effects, against unreasonable searches and seizures, shall not be violated, and no Warrants shall issue, but upon probable cause, supported by Oath or affirmation, and particularly describing the place to be searched, and the persons or things to be seized.
What does this mean??
This amendment is saying that no person, home, car or possession shall be searched without a reasonable suspicion. And with that suspicion they must get a warrant.
Why this picture?
This picture is mocking the fourth amendment by saying that "yeah, whatever, we don't really need a warrant...". When in reality, thanks to the fourth amendment, you cannot be searched without first reasonable suspicion and secondly a warrant.